Dr Torsten Kleffmann

Senior Research Fellow, Director of the Centre for Protein Research
  • Biochemistry Department
  • School of Biomedical Sciences
  • University of Otago
  • P.O. Box 56
  • 710 Cumberland St
  • Dunedin 9054 , New Zealand
  • Tel.: 64 3 479-7867
  • Fax: 64 3 479-7866
  • Email:torsten.kleffmann@otago.ac.nz


  • Torsten Kleffmann
  • 2015, OSMS Distinguished Research Support Staff Award

Selected Publications

J Wei, S Y Lau, C Blenkiron, Q Chen, J L James, T Kleffmann, M Wise, P R Stone, and L W Chamley., Trophoblastic debris modifies endothelial cell transcriptome in vitro: a mechanism by which fetal cells might control maternal responses to pregnancy., Sci Rep 2016 vol. 6 p. 30632., Link »

Mancy Tong, Torsten Kleffmann, Shantanu Pradhan, Caroline L Johansson, Joana DeSousa, Peter R Stone, Joanna L James, Qi Chen, and Larry W Chamley., Proteomic characterization of macro-, micro- and nano-extracellular vesicles derived from the same first trimester placenta: relevance for feto-maternal communication., Hum Reprod 2016 p. dew004.,

Egor P. Tchesnokov, Matthias Fellner, Eleni Siakkou, Torsten Kleffmann, Lois W Martin, Sekotilani Aloi, Iain L Lamont, Sigurd M Wilbanks, and Guy N L Jameson., The Cysteine Dioxygenase Homologue from Pseudomonas aeruginosa Is a 3-Mercaptopropionate Dioxygenase., J Biol Chem 2015 vol. 290 (40) pp. 24424-24437, Link »

A. von Zychlinski and T Kleffmann., Dissecting the proteome of lipoproteins: New biomarkers for cardiovascular diseases?., Translational Proteomics 2015 vol. 7 pp. 30-39, Link »

Paul L Guy, Richard Easingwood, Diana L Carne, and Torsten Kleffmann., Identification of two plant viruses using partial purification and mass spectrometry., Australasian Plant Disease Notes 2015 vol. 10 (1) p. 11., Link »

Joshua P Ramsay, Laura G L Tester, Anthony S Major, John T Sullivan, Christina D Edgar, Torsten Kleffmann, Jackson R Patterson-House, Drew A Hall, Warren P Tate, Michael F Hynes, and Clive W Ronson., Ribosomal frameshifting and dual-target antiactivation restrict quorum-sensing-activated transfer of a mobile genetic element., P Natl Acad Sci USA 2015 vol. 112 (13) pp. 4104-4109., Link »

Johnson, S. L., Villarroel, M., Rosengrave, P., Carne, A., Kleffmann, T., Lokman, P. M., & Gemmell, N. J. , Proteomic analysis of chinook salmon (Oncorhynchus tshawytscha) ovarian fluid., PLoS ONE. 9(8), e104155 (2014)., Link »

Chris J Pemberton, Maithri Siriwardena, Torsten Kleffmann, and A Mark Richards, CNP signal peptide fragments are present in the human circulation., Biochemical and Biophysical Research Communications 2014, Link »

Anne von Zychlinski, Michael Williams, Sally McCormick, and Torsten Kleffmann, Absolute quantification of apolipoproteins and associated proteins on human plasma lipoproteins., Journal of proteomics 2014, Link »

Yannick Marchalant, Philip W Brownjohn, Amandine Bonnet, Torsten Kleffmann, and John C Ashton, Validating Antibodies to the Cannabinoid CB2 Receptor: Antibody Sensitivity Is Not Evidence of Antibody Specificity., The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2014 vol. 62 (6) pp. 395-404, Link »

Richard J Souness, Torsten Kleffmann, Egor P. Tchesnokov, Sigurd M Wilbanks, Geoffrey B Jameson, and Guy N L Jameson, Mechanistic Implications of Persulfenate and Persulfide Binding in the Active Site of Cysteine Dioxygenase., Biochemistry 2013, 52 (43), pp 7606–7617, Link »

V Kumar, T Kleffmann, M B Hampton, M B Cannell, and C.C. Winterbourn, Redox proteomics of thiol proteins in mouse heart during ischemia/reperfusion using ICAT reagents and mass spectrometry, Free Radical Biology And Medicine 2013 vol. 58 pp. 109-117, Link »

Yoshio Nakatani, Torsten Kleffmann, Katrin Linke, Stephen M. Condon, Mark G Hinds, and Catherine L Day, Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase., The Biochemical Journal 2013 vol. 450 (3) pp. 629-638, Link »

C.J. Pemberton, M Siriwardena, T Kleffmann, P Ruygrok, S C Palmer, T.G. Yandle, and A.M. Richards, First identification of circulating prepro-A-type natriuretic peptide (preproANP) signal peptide fragments in humans: Initial assessment as cardiovascular biomarkers, Clinical Chemistry 2012 vol. 58 (4) pp. 757-767, Link »

Euan J Rodger, Rachel J Suetani, Gregory T Jones, Torsten Kleffmann, Alan Carne, Michael Legge, and Sally P A McCormick, Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis., PLoS ONE 2012 vol. 7 (1) p. e30383, Link »